officially supported by:
Austrian Society of Surgical Research
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Secretary
If you have questions concerning the organization of the event do not hestitate to contact our secretary.
Program
- 12:00 | Welcome: Bruno Podesser (A) and Hans Wojta (A)
- 12:15 – 14:00 | Resident Lunch: Meet the Editors
N. Bonaros (A): ICTVS
B. Podesser (A): EJCTS, JCVPT
Z. Papp (HU): European Heart Failure, ESC Heart Failure
J. Wojta (A): Cardiovasc Res, Thromb Haemost
F. Paneni (CH): European Heart Journal
Z. Ungvari (US/HU): Geroscience
- 14:00 – 14:30 | Coffee break
- 14:30 – 16:00 | Symposium I : Young Surgeons Forum
“Training the current and next generations”
Chair: Gollmann-Tepeköylü (A), J. Kalisnik (A)
D. Zimpfer (A) and M. Arnreiter (A)
M. Kreibich (G) and V. Banhegyi (G)
D. Santer (CH)G. Wieselthaler (USA/A)
organized by the Austrian and Swiss Young Surgeons Forum
- 16:00 – 16:30 | Coffee break
- 16:30 – 18:00 | Symposium II : (R)evolution in vascular grafts and tissue engineering
Chair: B. Winkler (A), H. Bergmeister (A)
Introduction lectures (15+5min):
K. Schneider (A): Advancements in Soft Tissue Engineering: Integrating Human Placenta-derived ECM Bioinks with novel 3D Bioprinting Strategies.
A. Marsano (CH): Exploring Troponin Release with In Vitro Cardiac Models.
Presentation (7+3min):
M. Grab (G): Multi-layered electrospun grafts for surgical repair: Biomimicking native ascending aortic compliance.
Julian Hubrich (G): Biogenic polymer-based patches for congenital cardiac surgery.
S. Rohringer (A): Material-specific modulation of the healing process of small-diameter vascular grafts.
S. Specht (A): Effect of different vascular graft materials on endothelialization using senescent endothelial cells at different inflammatory stages.
C. Radner (G): “Role of elastin in thoracic aortic aneurysm”
- 18:00 – 18:45 | Keynote Lecture I: G. Brandacher (A): Extended Subzero organ preservation using nature-inspired cryoprotectants
Chair: D. Chambers (UK), B. Podesser (A)
- 19:00 | Common dinner at the Restaurant in the Congress Center
Weissensee
- 08:00 – 09:30 | Symposium III: (R)evolution in myocardial and vascular protection
Chair: G. Szabó (G) and D. Santer (CH)
Introduction lectures (15+5min):
D. Chambers (GB): Myocardial or Endothelial Protection? Preferable both, but is that achievable with current cardioplegic solutions?
J. Pernow (S): Cardioprotective effects of red blood cells through activated soluble guanylate cyclase and release of cyclic GMP
F. Paneni (CH): Editing Chromatin to prevent Cardiometabolic Disease
Presentation (7+3min):
L. Saemann (G): Improved preservation of ventricular contractility of old donor hearts during static cold storage by the senomorphic agent ruxolitinib.
H. Lieder (G): Erythrocytes as carriers of cardioprotective signals: transfer of remote ischemic conditionings’ cardioprotection with erythrocytes from healthy human volunteers to isolated perfused rat hearts subjected to regional myocardial I/R.
J. Reiner (A): SGLT2 Inhibition Improves Cardiac Recovery and Metabolism following Cold Cardioplegic Arrest in Isolated Murine Hearts.
- 09:45 – 10:15 | Coffee Break
- 10:15 – 11:45 | Symposium IV: (R)evolution: Comorbidities: perioperative challenges
Chair: M. Kreibich (G) and D. Zimpfer (A)
Introduction lectures (15+5min):
M. Siegemund (CH): Sedation, Sleep and Delirium – the unhappy triad of Intensive Care.
Z. Papp (HU): Cardiotonic drugs in bridging to intervention: from molecular targets to clinical applicability.
Presentation (7+3min):
R. Mani (I): Nitric oxide administered in oxygenator during Ecmo improves ventricular-arterial coupling and decreases inflammation and oxidative stress in an experimental model of pulmonary arterial hypertension.
S. Martinazzi (I): Nitric oxide added to the ECMO circuit improves neuroprotection and cardiac function after cardiac arrest
E. Han (A): Comparison of bed-side high-sensitive troponin I with laboratory testing troponin T in patients with acute chest pain
M. Ernst (A): 5S-Study: Safe and Simple Single-Shot Pulmonary Vein Isolation with Pulsed Field Ablation using Sedation
K. Merse (HU): Investigation of the effects of the phosphodiesterase-5 inhibitor tadalafil in a rat model of uremic cardiomyopathy
- 11:45 – 13:00 | Symposium V: Moderated poster sessions I-III
Session I
Chair: C. Gollmann-Tepeköylü (A) and S.Hallström (A)
V. Banhegyi (G): Daily practice with the DryLab system improves surgical skills and promotes interest for cardiac surgery among visiting students.
V. Banhegyi (G): Regulation of tissue and circulating angiotensinconverting enzymes in cardiovascular diseases.
B. Gössinger (A): Neurologic recurrence after transcatheter PFO closure in patients with cryptogenic stroke.
A. Stampfer (A): Early inhibition of angiotensin converting enzyme after myocardial infarction ameliorates murine cardiac remodeling by modulating the expression of extracellular matrix genes.
K. Freystaetter (G): Type I and II Hybrid Aoritc Arch Repair as a safe alternative to open surgery in high-risk patients.
C. Herz (G): Hemodynamic In-vitro Analysis of Left Ventricular Assist Device Outflow Graft Orientations.
A. Szabó (HU): Stress may influence serum ACE activity.
R. Willixhofer (A): Caseous Calcification of the Mitral Annulus (CCMA), what to do and how to proceed. A Case Report.
M. Trutmann (CH): Non-invasive evaluation of the new-onset atrial fibrillation after cardiac surgery: a protocol for the BigMap study.
D. Hunziker (CH): Circadian melatonin rhythms in critically ill patients with delirium – A prospective single-centre observational proof-of-concept study.
Session II
Chair: K.Schneider (A) and A. Marsano (CH)
K. Mueller (D): A bioinspired microfiber-based mitral valve
scaffold via melt electrowriting.
S. Simon (D): Sustainability in Laboratory Practices: Challenges and Possibilities to Reach Environmental Stewardship in Research Facilities.
Z. Ocskay (HU): Characterization of the mechanisms leading to age-related changes of meningeal lymphatics.
B. Pelzmann (A): Preliminary data on a low molecular-weight factor isolated from human plasma which blocks L-type Ca2+ current in cardiomyocytes.
E. Han (A): Elevated tumor markers in long COVID patients with cardiovascular symptoms.
A. Goncalves (A): Cardiac Implications of Breast cancer: insights from a metabolic alterations.
S. Mosiołek (PL): Endothelial inflammation activates mitochondrial unfolded protein response (UPRmt): a possible novel target to modulate endothelial function.
P. Berkowicz (PL): Cardiac inflammation is activated in early but not in end-stage heart failure in Tgαq*44 mice.
A. Schmitt (A) : Interactions between Perivascular Adipose Tissue and Vascular Grafts in an in vitro bioreactor model.
F. Pointer (A): Design and evaluation of a microfluidic bioprinting system for 3D deposition of hierarchical vascular networks using an hpcECM-derived bioink.
Session III
Chair: A. Rungatscher (I) and F. Moscato (A)
T. Pintér (HU): Technical error or a new beginning? Exploring the issues in neprilysin biomarker research in heart failure.
J. Flexeder (G): Innovative Insights: Hemodynamics of Novel Heart Valve Prostheses Explored via 3D-printed Models and 4D MRI Analysis.
C. Riedmüller (A): In-vitro assessment of ECM-coated cardiac patches: Improving biocompatibility and cellular acceptance.
L. Weber (A): Crosstalk of Tenascin C and Lymphatics in Left Ventricular Hypertrophy-Induced Cardiac Remodeling.
E. Pichler (A): IL4 receptor signalling reduces atherosclerotic lesion size in a mouse model.
P. Gibler (A): Mouse strain specific response to a murine coronavirus respiratory infection reveals Kcnn4 as potential target or indicator of severity.
R. Losonczi (HU): Investigation of the effects of sex-based differences on the severity of trastuzumab-induced chronic cardiotoxicity in a rat model.
D. Volford (HU): Investigation of the effects of sex-based differences on the severity of paclitaxel-induced chronic cardiotoxicity in a rat model.
K. Kupecz (HU): Investigation of the effects of sex-based differences on the severity of doxorubicin-induced chronic cardiotoxicity in a rat model.
L. Wolner (A): The impact of the novel St Thomas’ Hospital polarizing cold blood cardioplegia on hemodynamic recovery in infarcted rat hearts.
- 15:30 – 17:00 | Symposium VI: Advancements in cardiovascular technology
and research
Chair: R. Seitelberger (A) and G.B. Luciani (I)
Introduction lectures (15+5min):
Z. Ungvari (US/HU): New Horizons in Cardiovascular Health: Geroscience´s Revolutionary Contributions to Future Cardiology
R. Seitelberger (A): The Future of Cardiac Surgery.
S. Globits (A): The Reality of Cardiovascular Medicine.
Presentation (7+3min):
S. Boeddu (G): Preventive Impella® Support in High-Risk Patients Undergoing Cardiac Surgery
U. Resch (G): Comparative proteomic analysis of human ventricular tissue of over 100 patients undergoing heart transplantation
M. Szczechowicz (G): Aortic Valve Replacement: Sutureless vs. Conventional Prosthesis in Complex Procedures – Insights from a Single-Center Experience
Z. Arnold (A): Secondary interventions after total arch replacement using the frozen elephant trunk prosthesis: open surgery versus endovascular techniques
- 20:00 | Common dinner at the “Bergbahnstüberl”
- 09:00 – 10:30 | Symposium VII: (R)evolution: Cardio-Oncology
Chair: J.Wojta (A) and A. Kiss (A)
Introduction lectures (15+5min):
J. Bergler-Klein (A): New ESC Cardio-oncology Guidelines.
S. Chlopicki (PL): Detrimental effects of anti-cancer drugs on endothelial function; towards personalized vasculo-oncology.
M. Maczewski (PL): Multiple myeloma is cardiotoxic through reduction of coronary flow reserve at the capillary level.
Presentation (7+3min):
P. Pokreisz (A): Development of spontaneous multifocal metastatic mammary tumours is accompanied by cardiac systolic and diastolic dysfunction in mice.
- 10:30 – 11:00 | Coffee break
- 11:00 - 12:30 | Symposium VIII: (R)evolution: Personalized medicine
Chair: S. Chlopicki (PL) and Z. Jakus (HU)
Introduction lectures (15+5min):
D. Tsiantoulas (A): Dissecting the functions of APRIL in cardiovascular diseases
F. Moscato (A): 3D Printing and Simulation for Personalization of Cardiovascular Devices, Implants and Surgical Procedures
Presentation (7+3min):
L. Grefen (G): From Concept to Clinical Reality: 3D Printing and Aortic Graft Development
J. Buech (G): Next step towards precision medicine in thoracic aortic disease – the potential of long non-coding RNAs
C. Spielvogel (A): Screening for abnormal cardiac scintigraphy uptake at risk for cardiac amyloidosis using deep learning: An international, multi-center, cross-tracer study
C. Dostal (A): High-throughput proteomic analysis unveils metabolic and mitochondrial signaling rewiring by chronic ivabradine treatment in Duchenne Muscular Dystrophy
- 12:45 | „Carl Apstein Award“
Closing remarks Bruno Podesser and Hans Wojta
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Bruno Podesser & Johann Wojta