The Rohringer Lab studies the integration of cardiovascular implants, with a primary focus on the role of the surrounding adipose tissue. The goal is to fully elucidate the function of adipose tissue following implantation and, through targeted therapeutic approaches, to modulate the properties of adipose tissue in such a way that the integration of the implants is significantly improved. This research is also intended to yield insights for the development of new biomaterials. The development of in vitro methods to investigate the interaction of biomaterials with vascular and adipose cells is another key focus of the lab.
We integrate advanced 2D and 3D cell culture models with molecular biology methods and findings from in vivo studies within a translational research context. The development of new in vitro methods to investigate the interaction of biomaterials with relevant cell types is another focus of the lab.
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Our Research Topics
The Rohringer Lab’s scientific focus is on investigating the complex interactions between biomaterials and tissue.
- Mechanisms of biomaterial-tissue interaction in cardiovascular implants
- Role of perivascular adipose tissue in inflammation, healing, and remodeling
- Extracellular vesicles as mediators of cell-to-cell communication following implantation
- Identification of new therapeutic targets to improve implant integration
Our work aims to gain new insights that will lead to long-term improvements in cardiovascular implants.
“In our research laboratory, we aim to identify pressing clinical needs in order to combine various disciplines and therapeutic approaches and thereby develop sustainable strategies to improve patients’ health.”
Cooperations
The Rohringer Lab works closely with national and international partners in both academic and non-academic settings:
- Christian Grasl (Medizinische Universität Wien, Zentrum für Medizinische Physik und Biomedizinische Technik)
- Wolfgang Holnthoner und Peter Dungel (Ludwig Boltzmann Institut für Traumatologie- Das Forschungszentrum in Kooperation mit der AUVA)
- Stefan Baudis (TU Wien, Institut für angewandte Synthesechemie)
- Silvio Kau-Strebinger (VetMedUni Wien, Institut für Morphologie)
- Dávid Kovács (Albert Szent-Györgyi Medical School, Department of Biochemistry, University of Szeged)
- Andreia Pereira (University of Porto, i3S)
If you are interested in new partnerships, please feel free to contact us at any time via email.