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  1. Center for Biomedical Research and Translational Surgery
  2. Research
  3. Cardiovascular Institute
  4. Research Groups
  5. Publications

Here you find a list of our publications of the last 5 years. Please select a research group to view the publications.

Research Group Schneider & Enayati

  1. Falkner F, Mayer SA, Heuer M, Brune J, Helt H, Bigdeli AK et al. Comparison of Decellularized Human Dermal Scaffolds versus Bovine Collagen/Elastin Matrices for in vivo Engineering of Axially Vascularized Soft Tissue Flaps in Rats. Plast Reconstr Surg 2023.
  2. Liang M, Li F, Wang Y, Chen H, Tian J, Zhao Z et al. Woven Vascular Stent-Grafts with Surface Modification of Silk Fibroin-Based Paclitaxel/Metformin Microspheres. Bioengineering (Basel) 2023; 10(4).
  3. Falkner F, Mayer SA, Thomas B, Zimmermann SO, Walter S, Heimel P et al. Acellular Human Placenta Small-Diameter Vessels as a Favorable Source of Super-Microsurgical Vascular Replacements: A Proof of Concept. Bioengineering (Basel) 2023; 10(3)
  4. Rohringer S#, Schneider KH#, Eder G, Hager P, Enayati M, Kapeller B et al. Chorion-derived extracellular matrix hydrogel and fibronectin surface coatings show similar beneficial effects on endothelialization of expanded polytetrafluorethylene vascular grafts. Mater Today Bio 2022; 14: 100262.
  5. Enayati M#, Schneider KH#, Almeria C, Grasl C, Kaun C, Messner B et al. S-nitroso human serum albumin as a nitric oxide donor in drug-eluting vascular grafts: Biofunctionality and preclinical evaluation. Acta Biomater 2021; 134: 276-288.
  6. Enayati M, Schneider KH, Almeria C, Grasl C, Kaun C, Messner B et al. S-nitroso human serum albumin as a nitric oxide donor in drug-eluting vascular grafts: Biofunctionality and preclinical evaluation. Acta Biomater 2021; 134: 276-288.
  7. Pereira AT, Schneider KH, Henriques PC, Grasl C, Melo SF, Fernandes IP et al. Graphene Oxide Coating Improves the Mechanical and Biological Properties of Decellularized Umbilical Cord Arteries. ACS Appl Mater Interfaces 2021; 13(28): 32662-32672.
  8. Pereira AT, Henriques PC, Schneider KH, Pires AL, Pereira AM, Martins MCL et al. Graphene-based materials: the key for the successful application of pHEMA as a blood-contacting device. Biomater Sci 2021; 9(9): 3362-3377.
  9. Enayati M, Puchhammer S, Iturri J, Grasl C, Kaun C, Baudis S et al. Assessment of a long-term in vitro model to characterize the mechanical behavior and macrophage-mediated degradation of a novel, degradable, electrospun poly-urethane vascular graft. J Mech Behav Biomed Mater 2020; 112: 104077.
  10. Eilenberg M, Enayati M, Ehebruster D, Grasl C, Walter I, Messner B et al. Long Term Evaluation of Nanofibrous, Bioabsorbable Polycarbonate Urethane Grafts for Small Diameter Vessel Replacement in Rodents. Eur J Vasc Endovasc Surg 2020; 59(4): 643-652.
  11. Schneider KH, Rohringer S, Kapeller B, Grasl C, Kiss H, Heber S et al. Riboflavin-mediated photooxidation to improve the characteristics of decellularized human arterial small diameter vascular grafts. Acta Biomater 2020; 116: 246-258.
  12. Schneider KH, Enayati M, Grasl C, Walter I, Budinsky L, Zebic G et al. Acellular vascular matrix grafts from human placenta chorion: Impact of ECM preservation on graft characteristics, protein composition and in vivo performance. Biomaterials 2018; 177: 14-26.
  13. S. Inglis, K.H. Schneider, J.M. Kanczler, H. Redl and R.O.C. Oreffo (2018). "Harnessing Human Decellularized Blood Vessel Matrices and Cellular Construct Implants to Promote Bone Healing in an Ex Vivo Organotypic Bone Defect Model." Adv Healthc Mater: e1800088. DOI: 10.1002/adhm.201800088
  14. S. A. Ferreira, M. S. Motwani, P. A. Faull, A. J. Seymour, T. T.L. Yu, M. Enayati, et al. , Bi-directional cell-pericellular matrix interactions direct stem cell fate, NATURE COMMUNICATIONS. 2018, DOI: 10.1038/s41467-018-06183-4

Research Group Podesser & Kiss

  1. Szabo PL, Marksteiner J, Ebner J, Dostal C, Podesser BK, Sauer J et al. Ivabradine acutely improves cardiac Ca handling and function in a rat model of Duchenne muscular dystrophy. Physiol Rep 2023; 11(7): e15664.
  2. Kronsteiner B, Zopf LM, Heimel P, Oberoi G, Kramer AM, Slezak P et al. Corrigendum: Mapping the functional anatomy and topography of the cardiac autonomic innervation for selective cardiac neuromodulation using MicroCT. Front Cell Dev Biol 2023; 11: 1193013.
  3. Kronsteiner B, Haberbusch M, Aigner P, Kramer AM, Pilz PM, Podesser BK et al. A novel ex-vivo isolated rabbit heart preparation to explore the cardiac effects of cervical and cardiac vagus nerve stimulation. Sci Rep 2023; 13(1): 4214.
  4. Hoebart C, Kiss A, Pilz PM, Szabo PL, Podesser BK, Fischer MJM et al. TRPA1 as Target in Myocardial Infarction. Int J Mol Sci 2023; 24(3).
  5. Dorninger F, Kiss A, Rothauer P, Stiglbauer-Tscholakoff A, Kummer S, Fallatah W et al. Overlapping and Distinct Features of Cardiac Pathology in Inherited Human and Murine Ether Lipid Deficiency. Int J Mol Sci 2023; 24(3).
  6. Ambrosini S, Montecucco F, Kolijn D, Pedicino D, Akhmedov A, Mohammed SA et al. Methylation of the Hippo effector YAP by the methyltransferase SETD7 drives myocardial ischaemic injury: a translational study. Cardiovasc Res 2023; 118(17): 3374-3385.
  7. Schaefer AK, Kiss A, Oszwald A, Nagel F, Acar E, Aliabadi-Zuckermann A et al. Single Donor Infusion of S-Nitroso-Human-Serum-Albumin Attenuates Cardiac Isograft Fibrosis and Preserves Myocardial Micro-RNA-126-3p in a Murine Heterotopic Heart Transplant Model. Transpl Int 2022; 35: 10057.
  8. Podesser BK, Kiss A. Editorial comments on 'Effects of ischaemic postconditioning in aortic valve replacement: a multicenter randomized controlled trial'. Eur J Cardiothorac Surg 2022; 61(5): 1153-1154.
  9. Pilz PM, Ward JE, Chang WT, Kiss A, Bateh E, Jha A et al. Large and Small Animal Models of Heart Failure With Reduced Ejection Fraction. Circ Res 2022; 130(12): 1888-1905.
  10. Nagel F, Schaefer AK, Goncalves IF, Acar E, Oszwald A, Kaiser P et al. The expression and role of tenascin C in abdominal aortic aneurysm formation and progression. Interact Cardiovasc Thorac Surg 2022; 34(5): 841-848.
  11. Mirna M, Paar V, Topf A, Kraus T, Sotlar K, Aigner A et al. A new player in the game: treatment with antagomiR-21a-5p significantly attenuates histological and echocardiographic effects of experimental autoimmune myocarditis. Cardiovasc Res 2022; 118(2): 556-572.
  12. Lu Y, Tian Y, Mou T, Zhou Y, Tian J, Yun M et al. Transient cardioprotective effects of remote ischemic postconditioning on non-reperfused myocardial infarction: longitudinal evaluation study in pigs. Int J Cardiol 2022; 355: 37-43.
  13. Kronsteiner B, Zopf LM, Heimel P, Oberoi G, Kramer AM, Slezak P et al. Mapping the functional anatomy and topography of the cardiac autonomic innervation for selective cardiac neuromodulation using MicroCT. Front Cell Dev Biol 2022; 10: 968870.
  14. Kramer AM, Kiss A, Heber S, Chambers DJ, Hallstrom S, Pilz PM et al. Normothermic blood polarizing versus depolarizing cardioplegia in a porcine model of cardiopulmonary bypass. Interact Cardiovasc Thorac Surg 2022; 35(1).
  15. Kiss A, Wu P, Schlederer M, Pilz PM, Szabo PL, Li J et al. Sympathetic nerve innervation and metabolism in ischemic myocardium in response to remote ischemic perconditioning. Basic Res Cardiol 2022; 117(1): 42.
  16. Haller PM, Goncalves IF, Acar E, Jager B, Pilz PM, Wojta J et al. Relationship between plasma Neuregulin-1 and cardiac function in patients with ST-elevation myocardial infarction. Rev Cardiovasc Med 2022; 23(2): 63.
  17. Haberbusch M, Kronsteiner B, Kramer AM, Kiss A, Podesser BK, Moscato F. Closed-loop vagus nerve stimulation for heart rate control evaluated in the Langendorff-perfused rabbit heart. Sci Rep 2022; 12(1): 18794.
  18. Aykac I, Podesser BK, Kiss A. Reverse remodeling in diabetic cardiomyopathy: the role of extracellular matrix. Minerva Cardiol Angiol 2022; 70(3): 385-392.
  19. Szabo PL, Ebner J, Koenig X, Hamza O, Watzinger S, Trojanek S et al. Cardiovascular phenotype of the Dmd(mdx) rat - a suitable animal model for Duchenne muscular dystrophy. Dis Model Mech 2021; 14(2).
  20. Szabo PL, Dostal C, Pilz PM, Hamza O, Acar E, Watzinger S et al. Remote Ischemic Perconditioning Ameliorates Myocardial Ischemia and Reperfusion-Induced Coronary Endothelial Dysfunction and Aortic Stiffness in Rats. J Cardiovasc Pharmacol Ther 2021; 26(6): 702-713.
  21. Perera-Gonzalez M, Kiss A, Kaiser P, Holzweber M, Nagel F, Watzinger S et al. The Role of Tenascin C in Cardiac Reverse Remodeling Following Banding-Debanding of the Ascending Aorta. Int J Mol Sci 2021; 22(4).
  22. Hoebart C, Rojas-Galvan NS, Ciotu CI, Aykac I, Reissig LF, Weninger WJ et al. No functional TRPA1 in cardiomyocytes. Acta Physiol (Oxf) 2021; 232(4): e13659.
  23. Bodi B, Pilz PM, Martha L, Lang M, Hamza O, Fagyas M et al. Alterations in ACE and ACE2 Activities and Cardiomyocyte Signaling Underlie Improved Myocardial Function in a Rat Model of Repeated Remote Ischemic Conditioning. Int J Mol Sci 2021; 22(20).
  24. Wernly B, Paar V, Aigner A, Pilz PM, Podesser BK, Forster M et al. Anti-CD3 Antibody Treatment Reduces Scar Formation in a Rat Model of Myocardial Infarction. Cells 2020; 9(2).
  25. Santer D, Nagel F, Goncalves IF, Kaun C, Wojta J, Fagyas M et al. Tenascin-C aggravates ventricular dilatation and angiotensin-converting enzyme activity after myocardial infarction in mice. ESC Heart Fail 2020; 7(5): 2113-2122.
  26. Pilz PM, Lang M, Hamza O, Szabo PL, Inci M, Kramer AM et al. Semi-Minimal Invasive Method to Induce Myocardial Infarction in Rats and the Assessment of Cardiac Function by an Isolated Working Heart System. J Vis Exp 2020; (160).
  27. Kiss A, Heber S, Kramer AM, Hackl M, Skalicky S, Hallstrom S et al. MicroRNA Expression Profile Changes after Cardiopulmonary Bypass and Ischemia/Reperfusion-Injury in a Porcine Model of Cardioplegic Arrest. Diagnostics (Basel) 2020; 10(4).
  28. Hamza O, Kiss A, Kramer AM, Trojanek S, Abraham D, Acar E et al. Tenascin C promotes valvular remodeling in two large animal models of ischemic mitral regurgitation. Basic Res Cardiol 2020; 115(6): 76.
  29. Hamza O, Kiss A, Kramer AM, Tillmann KE, Podesser BK. A novel percutaneous closed chest swine model of ischaemic mitral regurgitation guided by contrast echocardiography. EuroIntervention 2020; 16(6): e518-e522.
  30. Haller PM, Vargas KG, Haller MC, Piackova E, Wojta J, Gyongyosi M et al. Remote ischaemic conditioning for myocardial infarction or elective PCI: systematic review and meta-analyses of randomised trials. Eur Heart J Acute Cardiovasc Care 2020; 9(1_suppl): 82-92.
  31. Haller PM, Jager B, Piackova E, Sztulman L, Wegberger C, Wojta J et al. Changes in Circulating Extracellular Vesicles in Patients with ST-Elevation Myocardial Infarction and Potential Effects of Remote Ischemic Conditioning-A Randomized Controlled Trial. Biomedicines 2020; 8(7).
  32. Ebner J, Uhrin P, Szabo PL, Kiss A, Podesser BK, Todt H et al. Reduced Na(+) current in Purkinje fibers explains cardiac conduction defects and arrhythmias in Duchenne muscular dystrophy. Am J Physiol Heart Circ Physiol 2020; 318(6): H1436-H1440.
  33. Ebner J, Cagalinec M, Kubista H, Todt H, Szabo PL, Kiss A et al. Neuronal nitric oxide synthase regulation of calcium cycling in ventricular cardiomyocytes is independent of Ca(v)1.2 channel modulation under basal conditions. Pflugers Arch 2020; 472(1): 61-74.
  34. Wernly B, Mirna M, Rezar R, Prodinger C, Jung C, Podesser BK et al. Regenerative Cardiovascular Therapies: Stem Cells and Beyond. Int J Mol Sci 2019; 20(6).
  35. Santer D, Kramer A, Kiss A, Aumayr K, Hackl M, Heber S et al. St Thomas' Hospital polarizing blood cardioplegia improves hemodynamic recovery in a porcine model of cardiopulmonary bypass. J Thorac Cardiovasc Surg 2019; 158(6): 1543-1554 e8.
  36. Pilz PM, Podesser BK, Kiss A. Response to letter on "The role of remote ischemic perconditioning beyond myocardial infarction size reduction". Int J Cardiol 2019; 293: 53.
  37. Pilz PM, Hamza O, Gidlof O, Goncalves IF, Tretter EV, Trojanek S et al. Remote ischemic perconditioning attenuates adverse cardiac remodeling and preserves left ventricular function in a rat model of reperfused myocardial infarction. Int J Cardiol 2019; 285: 72-79.
  38. Pilz PM, Gidlof O, Podesser BK, Kiss A. Response to letter on "Post-translational modifications: Novel mechanism to clarify the cardioprotective effects of remote ischemic conditioning by Tang and Yang". Int J Cardiol 2019; 293: 51.
  39. Osmanagic-Myers S, Kiss A, Manakanatas C, Hamza O, Sedlmayer F, Szabo PL et al. Endothelial progerin expression causes cardiovascular pathology through an impaired mechanoresponse. J Clin Invest 2019; 129(2): 531-545.
  40. Nagel F, Santer D, Stojkovic S, Kaun C, Schaefer AK, Krssak M et al. The impact of age on cardiac function and extracellular matrix component expression in adverse post-infarction remodeling in mice. Exp Gerontol 2019; 119: 193-202.
  41. Kiss A, Podesser BK. Cardioprotection by PEDF: A novel form of GLUT4 membrane translocation to reduce myocardial ischemic injury. Int J Cardiol 2019; 288: 119-120.
  42. Kaniusas E, Kampusch S, Tittgemeyer M, Panetsos F, Gines RF, Papa M et al. Current Directions in the Auricular Vagus Nerve Stimulation I - A Physiological Perspective. Front Neurosci 2019; 13: 854.
  43. Kaniusas E, Kampusch S, Tittgemeyer M, Panetsos F, Gines RF, Papa M et al. Current Directions in the Auricular Vagus Nerve Stimulation II - An Engineering Perspective. Front Neurosci 2019; 13: 772.
  44. Goncalves IF, Acar E, Costantino S, Szabo PL, Hamza O, Tretter EV et al. Epigenetic modulation of tenascin C in the heart: implications on myocardial ischemia, hypertrophy and metabolism. J Hypertens 2019; 37(9): 1861-1870.
  45. Qi H, Soto-Gonzalez L, Krychtiuk KA, Ruhittel S, Kaun C, Speidl WS et al. Pretreatment With Argon Protects Human Cardiac Myocyte-Like Progenitor Cells from Oxygen Glucose Deprivation-Induced Cell Death by Activation of AKT and Differential Regulation of Mapkinases. Shock 2018; 49(5): 556-563.
  46. Podesser BK, Kreibich M, Dzilic E, Santer D, Forster L, Trojanek S et al. Tenascin-C promotes chronic pressure overload-induced cardiac dysfunction, hypertrophy and myocardial fibrosis. J Hypertens 2018; 36(4): 847-856.
  47. Kiss A, Shu H, Hamza O, Santer D, Tretter EV, Yao S et al. Argon preconditioning enhances postischaemic cardiac functional recovery following cardioplegic arrest and global cold ischaemia. Eur J Cardiothorac Surg 2018; 54(3): 539-546.
  48. Kiss A, Podesser BK. Low-dose of relaxin protects against arrhythmias and adverse left ventricle remodeling. Int J Cardiol 2018; 250: 60-61.

Research Group Bergmeister

  1. Falkner F, Mayer SA, Thomas B, Zimmermann SO, Walter S, Heimel P et al. Acellular Human Placenta Small-Diameter Vessels as a Favorable Source of Super-Microsurgical Vascular Replacements: A Proof of Concept. Bioengineering (Basel) 2023; 10(3).
  2. Falkner F, Mayer SA, Heuer M, Brune J, Helt H, Bigdeli AK et al. Comparison of Decellularized Human Dermal Scaffolds versus Bovine Collagen/Elastin Matrices for in vivo Engineering of Axially Vascularized Soft Tissue Flaps in Rats. Plast Reconstr Surg 2023.
  3. Rohringer S, Schneider KH, Eder G, Hager P, Enayati M, Kapeller B et al. Chorion-derived extracellular matrix hydrogel and fibronectin surface coatings show similar beneficial effects on endothelialization of expanded polytetrafluorethylene vascular grafts. Mater Today Bio 2022; 14: 100262.
  4. Pereira AT, Schneider KH, Henriques PC, Grasl C, Melo SF, Fernandes IP et al. Graphene Oxide Coating Improves the Mechanical and Biological Properties of Decellularized Umbilical Cord Arteries. ACS Appl Mater Interfaces 2021; 13(28): 32662-32672.
  5. Pereira AT, Henriques PC, Schneider KH, Pires AL, Pereira AM, Martins MCL et al. Graphene-based materials: the key for the successful application of pHEMA as a blood-contacting device. Biomater Sci 2021; 9(9): 3362-3377.
  6. Kallab M, Schuetzenberger K, Hommer N, Schafer BJ, Schmidl D, Bergmeister H et al. Bio-Distribution and Pharmacokinetics of Topically Administered gamma-Cyclodextrin Based Eye Drops in Rabbits. Pharmaceuticals (Basel) 2021; 14(5).
  7. Grasl C, Stoiber M, Rohrich M, Moscato F, Bergmeister H, Schima H. Electrospinning of small diameter vascular grafts with preferential fiber directions and comparison of their mechanical behavior with native rat aortas. Mater Sci Eng C Mater Biol Appl 2021; 124: 112085.
  8. Enayati M, Schneider KH, Almeria C, Grasl C, Kaun C, Messner B et al. S-nitroso human serum albumin as a nitric oxide donor in drug-eluting vascular grafts: Biofunctionality and preclinical evaluation. Acta Biomater 2021; 134: 276-288.
  9. Stoiber M, Grasl C, Frieberger K, Moscato F, Bergmeister H, Schima H. Impact of the testing protocol on the mechanical characterization of small diameter electrospun vascular grafts. J Mech Behav Biomed Mater 2020; 104: 103652.
  10. Schneider KH, Rohringer S, Kapeller B, Grasl C, Kiss H, Heber S et al. Riboflavin-mediated photooxidation to improve the characteristics of decellularized human arterial small diameter vascular grafts. Acta Biomater 2020; 116: 246-258.
  11. Enayati M, Puchhammer S, Iturri J, Grasl C, Kaun C, Baudis S et al. Assessment of a long-term in vitro model to characterize the mechanical behavior and macrophage-mediated degradation of a novel, degradable, electrospun poly-urethane vascular graft. J Mech Behav Biomed Mater 2020; 112: 104077.
  12. Eilenberg M, Enayati M, Ehebruster D, Grasl C, Walter I, Messner B et al. Long Term Evaluation of Nanofibrous, Bioabsorbable Polycarbonate Urethane Grafts for Small Diameter Vessel Replacement in Rodents. Eur J Vasc Endovasc Surg 2020; 59(4): 643-652.
  13. Ehrmann K, Potzmann P, Dworak C, Bergmeister H, Eilenberg M, Grasl C et al. Hard Block Degradable Polycarbonate Urethanes: Promising Biomaterials for Electrospun Vascular Prostheses. Biomacromolecules 2020; 21(2): 376-387.
  14. Bergmeister KD, Aman M, Kramer A, Schenck TL, Riedl O, Daeschler SC et al. Simulating Surgical Skills in Animals: Systematic Review, Costs & Acceptance Analyses. Front Vet Sci 2020; 7: 570852.
  15. Schneider KH, Enayati M, Grasl C, Walter I, Budinsky L, Zebic G et al. Acellular vascular matrix grafts from human placenta chorion: Impact of ECM preservation on graft characteristics, protein composition and in vivo performance. Biomaterials 2018; 177: 14-26.
  16. Djinovic Z, Pavelka R, Tomic M, Sprinzl G, Plenk H, Losert U et al. In-vitro and in-vivo measurement of the animal's middle ear acoustical response by partially implantable fiber-optic sensing system. Biosens Bioelectron 2018; 103: 176-181.

Research Group Hohensinner

  1. Vostatek R, Hohensinner P, Nopp S, Haider P, Englisch C, Pointner J et al. Association of telomere length and mitochondrial DNA copy number, two biomarkers of biological aging, with the risk of venous thromboembolism. Thromb Res 2023; 223: 168-173.
  2. Salzmann M, Platzer H, Mussbacher M, Derler M, Lenz M, Haider P et al. Staphylococcus aureus extracellular adherence protein (Eap) reduces immune cell phenotype in developing but not in established atherosclerotic lesions. Biochim Biophys Acta Mol Basis Dis 2023; 1869(3): 166616.
  3. Haider P, Kral-Pointner JB, Salzmann M, Moik F, Bleichert S, Schrottmaier WC et al. Interleukin-4 receptor alpha signaling regulates monocyte homeostasis. FASEB J 2022; 36(10): e22532.
  4. Lenz M, Salzmann M, Ciotu CI, Kaun C, Krychtiuk KA, Rehberger Likozar A et al. Pharmacologic modulation of intracellular Na(+) concentration with ranolazine impacts inflammatory response in humans and mice. Proc Natl Acad Sci U S A 2022; 119(29): e2207020119.
  5. Haider P, Hoberstorfer T, Salzmann M, Fischer MB, Speidl WS, Wojta J et al. Quantitative and Functional Assessment of the Influence of Routinely Used Cryopreservation Media on Mononuclear Leukocytes for Medical Research. Int J Mol Sci 2022; 23(3).
  6. Filik Y, Bauer K, Hadzijusufovic E, Haider P, Greiner G, Witzeneder N et al. PI3-kinase inhibition as a strategy to suppress the leukemic stem cell niche in Ph+ chronic myeloid leukemia. Am J Cancer Res 2021; 11(12): 6042-6059.
  7. van Ingen E, Foks AC, Woudenberg T, van der Bent ML, de Jong A, Hohensinner PJ et al. Inhibition of microRNA-494-3p activates Wnt signaling and reduces proinflammatory macrophage polarization in atherosclerosis. Mol Ther Nucleic Acids 2021; 26: 1228-1239.
  8. Salzmann M, Haider P, Kaun C, Brekalo M, Hartmann B, Lengheimer T et al. Innate Immune Training with Bacterial Extracts Enhances Lung Macrophage Recruitment to Protect from Betacoronavirus Infection. J Innate Immun 2022; 14(4): 293-305.
  9. Maier N, Gatterer C, Haider P, Salzmann M, Kaun C, Speidl WS et al. MiRNA Let-7a and Let-7d Are Induced by Globotriaosylceramide via NF-kB Activation in Fabry Disease. Genes (Basel) 2021; 12(8).
  10. Hohensinner PJ, Lenz M, Haider P, Mayer J, Richter M, Kaun C et al. Pharmacological inhibition of fatty acid oxidation reduces atherosclerosis progression by suppression of macrophage NLRP3 inflammasome activation. Biochem Pharmacol 2021; 190: 114634.
  11. Krychtiuk KA, Lenz M, Hohensinner P, Distelmaier K, Schrutka L, Kastl SP et al. Circulating levels of proprotein convertase subtilisin/kexin type 9 (PCSK9) are associated with monocyte subsets in patients with stable coronary artery disease. J Clin Lipidol 2021; 15(3): 512-521.
  12. Lenz M, Kaun C, Krychtiuk KA, Haider P, Brekalo M, Maier N et al. Effects of Nicorandil on Inflammation, Apoptosis and Atherosclerotic Plaque Progression. Biomedicines 2021; 9(2).
  13. Krychtiuk KA, Lenz M, Richter B, Hohensinner PJ, Kastl SP, Mangold A et al. Monocyte subsets predict mortality after cardiac arrest. J Leukoc Biol 2021; 109(6): 1139-1146.
  14. Haider P, Kral-Pointner JB, Mayer J, Richter M, Kaun C, Brostjan C et al. Neutrophil Extracellular Trap Degradation by Differently Polarized Macrophage Subsets. Arterioscler Thromb Vasc Biol 2020; 40(9): 2265-2278.
  15. Kazem N, Sulzgruber P, Thaler B, Baumgartner J, Koller L, Laufer G et al. CD8+CD28null T Lymphocytes are Associated with the Development of Atrial Fibrillation after Elective Cardiac Surgery. Thromb Haemost 2020; 120(8): 1182-1187.
  16. Krychtiuk KA, Richter B, Lenz M, Hohensinner PJ, Huber K, Hengstenberg C et al. Epinephrine treatment but not time to ROSC is associated with intestinal injury in patients with cardiac arrest. Resuscitation 2020; 155: 32-38.
  17. Demyanets S, Kaun C, Kaider A, Speidl W, Prager M, Oravec S et al. The pro-inflammatory marker soluble suppression of tumorigenicity-2 (ST2) is reduced especially in diabetic morbidly obese patients undergoing bariatric surgery. Cardiovasc Diabetol 2020; 19(1): 26.
  18. Hohensinner PJ, Mayer J, Kichbacher J, Kral-Pointner J, Thaler B, Kaun C et al. Alternative activation of human macrophages enhances tissue factor expression and production of extracellular vesicles. Haematologica 2021; 106(2): 454-463.
  19. Rega-Kaun G, Kaun C, Jaegersberger G, Prager M, Hackl M, Demyanets S et al. Roux-en-Y-Bariatric Surgery Reduces Markers of Metabolic Syndrome in Morbidly Obese Patients. Obes Surg 2020; 30(2): 391-400.
  20. Thaler B, Hohensinner PJ, Baumgartner J, Haider P, Krychtiuk KA, Schorgenhofer C et al. Protease-Activated Receptors 1 and 3 are Differentially Expressed on Human Monocyte Subsets and are Upregulated by Lipopolysaccharide Ex Vivo and In Vivo. Thromb Haemost 2019; 119(9): 1394-1402.
  21. Thaler B, Baik N, Hohensinner PJ, Baumgartner J, Panzenbock A, Stojkovic S et al. Differential expression of Plg-R(KT) and its effects on migration of proinflammatory monocyte and macrophage subsets. Blood 2019; 134(6): 561-567.
  22. Rega-Kaun G, Ritzel D, Kaun C, Ebenbauer B, Thaler B, Prager M et al. Changes of Circulating Extracellular Vesicles from the Liver after Roux-en-Y Bariatric Surgery. Int J Mol Sci 2019; 20(9).
  23. Mussbacher M, Salzmann M, Brostjan C, Hoesel B, Schoergenhofer C, Datler H et al. Cell Type-Specific Roles of NF-kappaB Linking Inflammation and Thrombosis. Front Immunol 2019; 10: 85.
  24. Hakansson KEJ, Goossens EAC, Trompet S, van Ingen E, de Vries MR, van der Kwast R et al. Genetic associations and regulation of expression indicate an independent role for 14q32 snoRNAs in human cardiovascular disease. Cardiovasc Res 2019; 115(10): 1519-1532.
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Forschungsgruppe Nina Pilat

  1. Fejes R, Lutnik M, Weisshaar S, Pilat N, Wagner KH, Stüger HP, Peake JM, Woodman RJ, Croft KD, Bondonno CP, Hodgson JM, Wolzt M, Neubauer O. (2024) Increased nitrate intake from beetroot juice over 4 weeks affects nitrate metabolism, but not vascular function or blood pressure in older adults with hypertension. Food Funct, 15(8):4065-4078. https://doi.org/10.1039/d3fo03749e
  2. Prickler L, Baranyi U, Mengrelis K, Weijler AM, Kainz V, Kratzer B, Steiner R, Mucha J, Rudoph E, Pilat N, Bohle B, Strobl H, Pickl WF, Valenta R, Linhart B, Wekerle T. (2023). Adoptive transfer of allergen-expressing B cells prevents IgE-mediated allergy. Front Immunol, 14:1286638. https://doi.org/10.3389/fimmu.2023.1286638
  3. Steiner, R., & Pilat, N. (2023). The potential for Treg-enhancing therapies in transplantation. Clin Exp Immunol, 211(2), 122-137. https://doi.org/10.1093/cei/uxac118
  4. Pilat, N. (2023). Inadvertent stem cell transfer demonstrating a way for tolerance induction. Kidney Int, 103(1), 21-22. https://doi.org/10.1016/j.kint.2022.11.007
  5. Pilat, N., Steiner, R., & Sprent, J. (2023). Treg Therapy for the Induction of Immune Tolerance in Transplantation-Not Lost in Translation? Int J Mol Sci, 24(2). https://doi.org/10.3390/ijms24021752
  6. Pilat, N., Issa, F., Luo, X., Chong, A., Bromberg, J., & Kotsch, K. (2022). Joining Forces in Basic Science: ITS Meeting 2.0. Transpl Int, 35, 10843. https://doi.org/10.3389/ti.2022.10843
  7. Pilat, N., Wekerle, T., Geissler, E. K., & Sprent, J. (2022). Editorial: Immunological Tolerance in Transplantation: More Than Deletion. Front Immunol, 13, 959115. https://doi.org/10.3389/fimmu.2022.959115
  8. Unger, L. W., Muckenhuber, M., Mahr, B., Schwarz, C., Pilat, N., Granofszky, N., Regele, H., & Wekerle, T. (2022). Chronic CD40L blockade is required for long-term cardiac allograft survival with a clinically relevant CTLA4-Ig dosing regimen. Front Immunol, 13, 1060576. https://doi.org/10.3389/fimmu.2022.1060576
  9. Steiner, R., Weijler, A. M., Wekerle, T., Sprent, J., & Pilat, N. (2021). Impact of Graft-Resident Leucocytes on Treg Mediated Skin Graft Survival. Front Immunol, 12, 801595. https://doi.org/10.3389/fimmu.2021.801595
  10. Pilat, N., Lefsihane, K., Brouard, S., Kotsch, K., Falk, C., Steiner, R., Thaunat, O., Fusil, F., Montserrat, N., Amarelli, C., & Casiraghi, F. (2021). T- and B-cell therapy in solid organ transplantation: current evidence and future expectations. Transpl Int, 34(9), 1594-1606. https://doi.org/10.1111/tri.13972
  11. Mahr, B., Pilat, N., Granofszky, N., Muckenhuber, M., Unger, L. W., Weijler, A. M., Wiletel, M., Steiner, R., Dorner, L., Regele, H., & Wekerle, T. (2021). Distinct roles for major and minor antigen barriers in chimerism-based tolerance under irradiation-free conditions. Am J Transplant, 21(3), 968-977. https://doi.org/10.1111/ajt.16177
  12. Schwarz, C., Mahr, B., Muckenhuber, M., Weijler, A. M., Unger, L. W., Pilat, N., Latus, M., Regele, H., & Wekerle, T. (2021). In vivo Treg expansion under costimulation blockade targets early rejection and improves long-term outcome. Am J Transplant, 21(11), 3765-3774. https://doi.org/10.1111/ajt.16724
  13. Pilat, N., & Sprent, J. (2020). Treg Therapies Revisited: Tolerance Beyond Deletion. Front Immunol, 11, 622810. https://doi.org/10.3389/fimmu.2020.622810
  14. Weijler, A. M., Mucha, J., Farkas, A. M., Baranyi, U., Pilat, N., Cho, A., Muckenhuber, M., Hopf, S., Wahrmann, M., Linhart, B., Valenta, R., & Wekerle, T. (2020). Methods to Detect MHC-Specific IgE in Mice and Men. Front Immunol, 11, 586856. https://doi.org/10.3389/fimmu.2020.586856
  15. Pilat, N., Wiletel, M., Weijler, A. M., Steiner, R., Mahr, B., Warren, J., Corpuz, T. M., Wekerle, T., Webster, K. E., & Sprent, J. (2019). Treg-mediated prolonged survival of skin allografts without immunosuppression. Proc Natl Acad Sci U S A, 116(27), 13508-13516. https://doi.org/10.1073/pnas.1903165116
  16. Farkas, A. M., Baranyi, U., Bohmig, G. A., Unger, L., Hopf, S., Wahrmann, M., Regele, H., Mahr, B., Schwarz, C., Hock, K., Pilat, N., Kristo, I., Mraz, J., Lupinek, C., Thalhamer, J., Bond, G., Kuessel, L., Wlodek, E., Martin, J., . . . Wekerle, T. (2019). Allograft rejection is associated with development of functional IgE specific for donor MHC antigens. J Allergy Clin Immunol, 143(1), 335-345 e312. https://doi.org/10.1016/j.jaci.2018.06.034
  17. Mahr, B., Pilat, N., Granofszky, N., Wiletel, M., Muckenhuber, M., Maschke, S., Hock, K., & Wekerle, T. (2019). Hybrid resistance to parental bone marrow grafts in nonlethally irradiated mice. Am J Transplant, 19(2), 591-596. https://doi.org/10.1111/ajt.15146
  18. Pilat, N., Mahr, B., Gattringer, M., Baranyi, U., & Wekerle, T. (2018). CTLA4Ig Improves Murine iTreg Induction via TGFβ and Suppressor Function In Vitro. J Immunol Res, 2018, 2484825. https://doi.org/10.1155/2018/2484825
  19. Pilat, N., Sabler, P., Klaus, C., Mahr, B., Unger, L., Hock, K., Wiletel, M., Schwarz, C., Kristo, I., Regele, H., & Wekerle, T. (2018). Blockade of adhesion molecule lymphocyte function-associated antigen-1 improves long-term heart allograft survival in mixed chimeras. J Heart Lung Transplant, 37(9), 1119-1130. https://doi.org/10.1016/j.healun.2018.03.016