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Research Group Bergmeister

Small-diameter vascular grafts

Over the past decades, various materials and surface modifications have been investigated to improve the patency rates of synthetic implants. Despite intensive efforts, autologous, patient-derived vascular grafts remain superior to artificial biomaterials. Our goal is to develop new implants with good long-term function for the replacement of small caliber vessels.

Biomaterials from extracellular matrix (ECM)

Biological materials consisting of the extracellular matrix have a beneficial effect on cell migration and growth due to their structure and composition. Therefore, extracellular matrix products are a very good starting material for the production of biomaterials for tissue regeneration. Besides animal tissue, human placenta has great advantages as a tissue source due to its human origin and its availability as a clinical waste product.

Biomaterial testing

Biocompatibility and long-term function of biomaterials are the most important factors for successful application of implants. In addition to conventional testing of biomaterials, we are developing new assessment methods to better characterize the interactions between recipient and biomaterial.

  • Zentrum für Biomedizinische Physik und Biomedizinische Technik, Medizinische Universität Wien : H. Schima, C. Grasl, M. Stoiber
  • Institut für Angewandte Synthetische Chemie, Technische Universität Wien: R. Liska, S. Baudis, K. Ehrmann
  • Klinische Abteilung für Kardiologie, Medizinische Universität Wien: Johann Wojta, Phillip Hohensinner
  • Universitätsklinik für Frauenheilkunde Medizinische Universität Wien: H. Kiss        
  • Universitätsklinik für Kinder- und Jugendheilkunde, Medizinische Universität Wien: K. Kratochwil
  • Department für Pathobiologie, Veterinärmedizinische Universität: I. Walter
  • Ludwig Boltzmann Institut für experimentelle und klinische Traumatologie: H.Redl
  • Technikum Vienna: A. Teuschl
  • Medizinische Universität Graz: S. Hallström
  • Universität Porto, INEB, Portugal: I. Concalves
  • Universität Heidelberg, BG — Unfallklinik Ludwigshafen, Deutschland: U. Kneser
  • Tufts University, USA: D. Kaplan